Paola Peluso

Paola Peluso is a tenured Researcher at the Institute of Biomolecular Chemistry (ICB) (Sassari, Italy), National Research Council (CNR). She received her Laurea degree in Chemistry from the University of Pisa (Italy), and her Ph.D. in Chemical Sciences from the University Ca’ Foscari Venice (Venice, Italy) Since 2008, she has started her independent career at the ICB-CNR where she leads the Unit of Enantioselective Chromatography and Molecular Recognition. Her research activity mainly concerns liquid-phase enantioseparations and related recognition mechanisms, computational and experimental identification and quantification of noncovalent interactions, electrostatic potential analysis and characterization of σ– and π-hole interactions in HPLC environment. She is author and co-author of 66 papers in international journals (H-index 20), of two book chapters (“Fundamentals of enantioselective liquid chromatography” and “Application of enantioselective liquid chromatography”), included in Liquid Chromatography (Elsevier, 2023), and numerous communications at international congresses. Invited and keynote speaker at international congresses and meeting, Scientific Committee Member of 11^th Annual Symposium on Physical and Analytical Chemistry (Tbilisi, Georgia, 2023), and Editorial Board Member of Electrophoresis (Wiley) (IF 3.595) and the Journal of Pharmaceutical and Biomedical Analysis Open (Elsevier). Principal Investigator of the Bilateral Project Italy-Georgia 2023-2024 “Experimental and theoretical studies on mechanisms and noncovalent interactions involved in liquid-phase enantioseparations”. Participant in the Project ASYMHOLE (Asymmetric Catalysis Promoted by Sigma-Hole Interactions) funded by Agence Nationale de la Recherche (ANR). Main collaborations: Prof. Bezhan Chankvetadze (University of Tbilisi, Georgia), Dr. Victor Mamane (CNRS, Université de Strasbourg, France), Prof. Gerhard K.E. Scriba (Friedrich Schiller University, Jena, Germany), Dr. Carlo Gatti (SCITEC-CNR, Milan), Prof. Sergio Cossu (Università Ca’ Foscari Venezia, Venice). In 2023, Dr. Peluso achieved the national scientific qualification as associate professor in the Italian higher education system for the disciplinary field 03/A1 Analytical and Physical Chemistry.

1. Peluso, P.; Landy, D.; Nakhhle, L.; Dallocchio, R.; Dessì, A.; Krait, S.; Salgado, A.; Chankvetadze, B.; Scriba, G. K. E. Isothermal titration calorimetry and molecular modeling study of the complex formation of daclatasvir by γ-cyclodextrin and trimethyl-β-cyclodextrin. Carbohydrate Polymers 2023, 313, 120870. DOI: 10.1016/j.carbpol.2023.120870.
2. Sechi, B.; Dessì, A.; Gatti, C.; Dallocchio, R.; Chankvetadze, B.; Cossu, S.; Mamane, V; Pale, P.; Peluso, P. Unravelling functions of halogen substituents in the enantioseparation of halogenated planar chiral ferrocenes on polysaccharide-based chiral stationary phases: experimental and electrostatic potential analyses. J. Chromatogr. A 2022, 1673, 463097 (invited article on Special Issue Enantioseparations 2022). DOI: 10.1016/j.chroma.2022.463097. https://pubmed.ncbi.nlm.nih.gov/35544969/
3. Peluso, P.; Chankvetadze, B. Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers. Chem. Rev. 2022, 122, 13235-13400. DOI: 10.1021/acs.chemrev.1c00846. https://pubmed.ncbi.nlm.nih.gov/35917234/
4. Peluso, P.; Chankvetadze, B. The molecular bases of chiral recognition in 2-(benzylsulfinyl) benzamide enantioseparation. Anal. Chim. Acta 2021, 1141, 194-205. DOI: 10.1016/j.aca.2020.10.050. https://pubmed.ncbi.nlm.nih.gov/33248652/
5. Peluso, P.; Dessì, A.; Dallocchio, R.; Sechi, B.; Gatti, C.; Chankvetadze, B.; Mamane, V.; Weiss, R.; Pale, P.; Aubert, E.; Cossu, S. Enantioseparation of 5,5’-dibromo-2,2’-dichloro-3-selanyl-4,4’-bipyridines on polysaccharide-based chiral stationary phases: exploring chalcogen bonds in liquid-phase chromatography. Molecules 2021, 26, 221 (Special Issue Chiral Stationary Phases for Enantioseparations: Fundamentals, Preparation, Methods, Applications and Chiral Recognition Mechanisms). DOI: 10.3390/molecules26010221. https://pubmed.ncbi.nlm.nih.gov/33406753/