The gut microbiota-brain axis refers to the bidirectional communication network between the central nervous system, including the brain, and the enteric nervous system, which is the nervous system of the gastrointestinal tract. This complex network involves multiple pathways and systems, including the immune system, the endocrine system, and the neural system, and is thought to play a crucial role in maintaining homeostasis and promoting health. Research suggests that alterations in the gut microbiota, also known as dysbiosis, may contribute to various diseases, including disorders of the brain and nervous system. For example, studies have implicated the gut microbiota in the pathogenesis of neuropsychiatric disorders such as schizophrenia and autism spectrum disorder. Additionally, research has suggested a potential role for the gut microbiota in neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease.
The exact mechanisms by which the gut microbiota influences the brain and contributes to disease are not fully understood but may involve the production of neuroactive compounds, modulation of the immune system, and influence on the blood-brain barrier. The potential for modulating the gut microbiota to prevent or treat diseases of the brain and nervous system is an area of active research. The symposium organized by Dr. Fabio Iannotti (Senior Researcher at ICB – Pozzuoli), and Neapolitan Brain Group – NBG led by President Prof. Ennio Del Giudice (Pediatric Neuropsychiatrist) presents an excellent opportunity to exchange knowledge and establish new collaborations between basic and clinical scientists on this fascinating topic.
The event is open to all at no cost.
