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Mass spectrometry

Instrumentation

Advanced technologies for the identification, separation and determination of the accurate molecular weight of organic molecules with applications in the biomedical field through untargeted and targeted approaches.

  • Micro-qToF mass spectrometer (Waters) with an electrospray ionization (ESI) source and coupled with a Waters Alliance HPLC system (research site of Pozzuoli)
  • Waters ACQUITY UPLC System QqQ – ABSciex (research site of Pozzuoli)
  • High resolution mass spectrometer Q-Exactive Hybrid Quadrupole-Orbitrap Mass Spectrometer (Thermo Scientific) on-line with a UHPLC apparatus Infinity 1290 (Agilent Technologies, Santa Clara, CA, USA). GC-MS THERMO (research site of Pozzuoli)
  • LC-APCI-MS: (Shimadzu Corporation): HPLC (LC-10ADVP) coupled to single quadrupole mass spectrometer Shimadzu (LCMS-2020) with APCI source (research site of Pozzuoli)
  • LC-MS/MS: high mass accuracy HPLC/IT-TOF (Shimadzu Corporation) system (Resolving Power 10,000 FWHM at 1000 m/z) (research site of Pozzuoli)
  • ion-trap GC–MS instrument (Thermo ITQ 700 Mass spectrometer interfaced with Thermo Focus GC Polaris Q (Thermo Scientific) (research site of Pozzuoli)
  • Liquid chromatography-tandem high-resolution mass spectrometer (LC-HRMS) UPLC Ultimate 3000 (Thermo Fisher-Dionex San Jose, CA, USA) system equipped with a HESI-II electrospray source to a Q-Exactive-Orbitrap™-based mass spectrometer (all from Thermo Scientific, San Jose, CA, USA) (research site of Sassari)
  • Agilent LC-MS system, composed of 1260 INFINITY II HPLC system + G6130B single quadrupole detector (research site of Padova*)
* LOAN FOR USE INSTRUMENTATION FROM RESEARCH CONTRACT WITH FRESENIUS IPSUM
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