Maria Cristina Sini

Maria Cristina Sini is graduated in Biological Science at University of Sassari in 2000 and received her PhD Degree in Biochemistry, Biology and Molecular Biotechnology at the University of Sassari in 2006. She is currently researcher at Institute of Biomolecular Chemistry (ICB), CNR and affiliated with IRGB, CNR.

Winner of a national research grant from the Italian Melanoma Intergroup (IMI) as principal investigator and of the Advanced Training Program of the Sardinia Region “Master and Back” too. She contributes as co-investigator in several national and international scientific research projects. She is currently member of the International Consortium ENIGMA (Evidence-based Network for the Interpretation of Germline Mutant Alleles) and member of the IMI (Italian Melanoma Intergroup) scientific committee .

Her research activity is actually based on clinical cancer genetics and translational medicine aimed to identify new molecular targets for the development of targeted therapy using Next Generation Sequencing (NGS) technologies with multigene panels. She is author of several peer-reviewed publications and several book chapters.

Manca, A, Sini M.C., Cesinaro, AM, Portelli, F, Urso, C, Lentini, M, Cardia, R, Alos, L, Cook, M, Simi, S, Paliogiannis, P, De Giorgi, V, Cossu, A, Palmieri, G, Massi, D. NGS-Based Analysis of Atypical Deep Penetrating Nevi. CANCERS (2021), ISSN: 2072-6694, DOI: 10.3390/cancers13123066

https://biblioproxy.cnr.it:3009/wos/woscc/full-record/WOS:000666749300001

https://pubmed.ncbi.nlm.nih.gov/34205480/

Sini, M.C., Doneddu, V., Paliogiannis P., Casula M., Colombino M., Manca A., Botti G., Ascierto, PA., Lissia A., Cossu A., Palmieri G. Genetic alterations in main candidate genes during melanoma progression. ONCOTARGET (2018), vol. 9, p. 8531-8541, ISSN: 1949-2553,

DOI: 10.18632/oncotarget.23989

https://pubmed.ncbi.nlm.nih.gov/29492214/

Liu, Pin, Ge, Mengmeng, Hu, Junjie, Li, Xiaolei, Che, Li, Sun, Kun, Cheng, Lili, Huang, Yuedong, Pilo, Maria G, Cigliano, Antonio, Pes, Giovanni M, Pascale, Rosa M, Brozzetti, Stefania, Vidili, Gianpaolo, Porcu, Alberto, Cossu, Antonio, Palmieri, Giuseppe, Sini, Maria C, Ribback, Silvia, Dombrowski, Frank, Tao, Junyan, Calvisi, Diego F, Chen, Ligong, Chen, Xin. A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis. HEPATOLOGY (2017), vol. 66, p. 167-181, ISSN: 1527-3350, DOI: 10.1002/hep.29183

https://biblioproxy.cnr.it:3009/wos/woscc/full-record/WOS:000403883100016

https://pubmed.ncbi.nlm.nih.gov/28370287/

Colombino M, Sini M.C., Lissia A, De Giorgi V, Stanganelli I, Ayala F, Massi D, Rubino C, Manca A, Paliogiannis P, Rossari S, Magi S, Mazzoni L, Botti G, Capone M, Palla M, Ascierto PA, Cossu A, Palmieri G, Italian Melanoma Intergroup (IMI). Discrepant alterations in main candidate genes among multiple primary melanomas . JOURNAL OF TRANSLATIONAL MEDICINE (2014), ISSN: 1479-5876, DOI: 10.1186/1479-5876-12-117

https://biblioproxy.cnr.it:3009/wos/woscc/full-record/WOS:000336931000001

https://pubmed.ncbi.nlm.nih.gov/24885594/

M.C. Sini , A Manca, A Cossu, M Budroni, G Botti, P A Ascierto, F Cremona, A Muggiano, S D’Atri, M Casula, P Baldinu, G Palomba, A Lissia, F Tanda, G Palmieri. Molecular alterations at chromosome 9p21 in melanocytic naevi and melanoma. BRITISH JOURNAL OF DERMATOLOGY (2008), vol. 158(2), p. 243-250, ISSN: 0007-0963, DOI: 10.1111/j.1365-2133.2007.08310.x

https://biblioproxy.cnr.it:3009/wos/woscc/full-record/WOS:000252495000006

https://pubmed.ncbi.nlm.nih.gov/18028495/