Valentina Giglio

Valentina Giglio, graduated with honors in Biomolecular Chemistry from the University of Catania in 2012. In 2016, she achieved her International PhD in Translational Biomedicine from the same university, focusing her research on the synthesis and characterization of cyclodextrin-based polymeric derivatives as drug delivery systems. During her PhD, she spent a period as visiting PhD student at the Institut de Science et d’Ingénierie Supramoléculaires at the University of Strasbourg, working on the synthesis and functionalization of mesoporous silica nanoparticles for drug delivery. After completing her PhD, she got a Post-Doc fellowship at the same french research institute to continue her research on nanoparticle functionalization. In 2017, she came back to Italy as research fellow until 2021 at the Organic Mass Spectrometry Laboratory at the Department of Chemical Sciences at the University of Catania, where she gained extensive expertise in mass spectrometry, both for proteomic studies and for the determination of small molecules in biological matrices. From 2021 to 2023, she worked as researcher at the Innovative Development Department at Fidia Farmaceutici, developing new hyaluronic acid-based drugs. Since July 2023, she has been a Level III researcher on a fixed-term contract at ICB-CNR in Catania, where she focuses on the synthesis and characterization of macroporous cryogels based on calixarene macrocycles for the removal of pollutants from wastewater and air.

• Mass spectrometry for qualitative and quantitative analysis of protein and small molecules
• Organic synthesis
• Synthesis of polymeric and inorganic nanomaterial
• Synthesis of macroporous polymeric material
• Targeted drug delivery systems

1. Giglio V., Zagni, C., Spina E.T.A., Cunsolo F., Carroccio S.C. “Polyvinylimidazole-Based Cryogel as an Efficient Tool for the Capture and Release of Oleuropein in Aqueous Media” Polymers 2024, 16, 2339.
2. Bognanni N., Scuderi C., Giglio V., Spiteri F., La Piana L., Condorelli D., Barresi V., Vecchio G. “Cyclodextrin Dimers Functionalized with Biotin as Nanocapsules for Active Doxorubicin Delivery Against MCF-7 Breast Cell Line” ChemMedChem 2024 Sep 9:e202400368.
3. Giglio V., Varela-Aramburuc S., Travaglini L., Fiorini F., Seeberger P. H., Maggini L, De Cola L, “Reshaping silica particles: Mesoporous nanodiscs for bimodal delivery and improved cellular uptake” Eng. J. 2018, 340, 148-154.
4. Giglio V., Viale, M., Bertone, V., Maric, I., Vaccarone, R., Vecchio, G., “Cyclodextrin polymers as nanocarriers for sorafenib” Invest New Drug 2018, 36, 370-379.
5. Giglio V., Sgarlata C., Vecchio G., ”Novel amino-cyclodextrin cross-linked oligomer as efficient carrier for anionic drugs: A spectroscopic and nanocalorimetric investigation”, RSC Adv, 2015, 5, 16664-16671.

  RESEARCH SITE OF CATANIA

   v.giglio@icb.cnr.it

   095 7338335